392 TARGETING ONE-CARBON METABOLISM IN BRAIN CANCER

392 Targeting One-Carbon Metabolism in Brain Cancer

OBJECTIVES/GOALS: Glioblastoma (GBM) is the most malignant brain tumor in adults and remains incurable with an average survival of 15 months after diagnosis.There is great need for treatment options without side effects that are devastating to the quality of life for patients.GBM tumors can circumvent cellular damage by upregulating antioxidant pro

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CONCEPTUAL BASES OF FORMATION OF COMPETENCE POTENTIAL OF LIVING LABOUR UNDER THE INFLUENCE OF CYBER-PHYSICAL SYSTEMS

The relevance of the issue of the competence potential of living labour is due to the need for evolutionary changes in the labour potential of the workforce as a response to the transformation of embodied labour in the context of the digitalisation of the economy.The aim of the research is to substantiate the conceptual foundations for the formatio

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A new method for fluid input into a hybrid synthetic jet actuator

A new principle of flow rectification for hybrid synthetic jet actuators is introduced in this paper.As is well known, the flow Saddles rectification can be best accomplished by means of fluidic diodes.Novelty of the present study are fluidic diodes with two mutually opposed nozzles.Interaction between the periodic jet flows from the nozzles causes

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